Stenbolone
A non-aromatising DHT-derived injectable anabolic (2-methyl-1-dehydro-DHT), closely related to methenolone (Primobolan). Marketed briefly as the acetate (Anatrofin/Stenbolone), it is a mild, dry, non-estrogenic compound that never gained a foothold and is essentially uncharacterised in modern studies.
01 Overview
Stenbolone is 2-methyl-5-alpha-androst-1-en-17-beta-ol-3-one, a dihydrotestosterone-derived steroid structurally analogous to methenolone but with a 2-methyl group in place of methenolone's 1-methyl. Like its cousin it does not aromatise and is not 17-alpha-alkylated, giving a mild, non-estrogenic, non-hepatotoxic profile. It was sold as the acetate ester (Anatrofin, Stenbolone) for a short period.
It is regarded as a lean, 'dry' compound producing modest quality gains without water retention, favoured in vintage circles for cutting-style use. It never achieved commercial success and disappeared, so essentially no controlled human data exist; its reputation is built on structural analogy to Primobolan and scattered anecdote.
02 Mechanism
Androgen receptor agonist derived from DHT. The saturated A-ring and 2-methyl substitution prevent aromatisation, so it produces no estrogenic activity and yields a mild, non-water-retaining anabolic effect.
03 Dosing
| Tier | Dose | Route | Notes |
|---|---|---|---|
| Anecdotal (acetate) | 200–400 mg/wk | IM | Short ester requires frequent injection; no controlled data. |
Ester comparison
| Ester | Half-life | Injection freq. | Testosterone by mass |
|---|
04 Effects
| Effect | Magnitude | Evidence | |
|---|---|---|---|
| Lean, dry gainsQuality lean-mass gain without water retention, reported anecdotally. | Anecdotal | ||
| No estrogenic activityDoes not aromatise, so no estrogenic side effects from the drug. | Preclinical |
05 Side effects
| Effect | Severity | Frequency | Evidence | Countermeasures |
|---|---|---|---|---|
| Androgenic effectsAcne, oily skin; hair-loss and virilisation risk from a DHT-derived androgen. | Mild | Dose-dependent | Anecdotal | |
| HPTA suppressionSuppression of endogenous testosterone. | Moderate | Expected | Anecdotal | |
| Frequent injection burdenThe short acetate ester requires very frequent injections. | Mild | Inherent to acetate | Anecdotal |