Anabolic steroidAndrogen19-nortestosteroneDesigner steroid

Dienolone

Also known as Dienolone · Estra-4,9-dien-3-one derivative

Written by enwyReviewed 15 Jul 20261 sources0 comments

A 19-nortestosterone-derived steroid with an added ring double bond, related to trenbolone and dienogest chemistry. Investigated briefly in mid-century animal work and later appearing as a prohormone target; virtually no human data.

01 Overview

Dienolone (17beta-hydroxyestra-4,9-dien-3-one is the closely related trienolone; dienolone denotes the estra-4,9-dien-3-one alcohol family) belongs to the 19-nor group and is chemically adjacent to trenbolone. It has been discussed as a designer/prohormone compound because precursors can convert toward this scaffold.

Human pharmacology is effectively absent. What is known derives from animal androgen bioassays and structural inference from the trenbolone family.

02 Mechanism

19-nortestosterone-class androgen-receptor agonist; the diene structure resists aromatisation and promotes strong AR-mediated anabolic signalling similar to trenbolone.

03 Dosing

Tier	Dose	Route	Notes
Anecdotal	10–30 mg/day	Oral	No validated dosing; anecdote only.

Ester comparison

Ester	Half-life	Injection freq.	Testosterone by mass

04 Effects

Effect	Magnitude	Evidence
Anabolic activityAnimal assays and structural analogy to trenbolone suggest strong AR-mediated anabolism.	unquantified	Preclinical
Non-estrogenic profileDiene structure is not a substrate for aromatase.	n/a	Preclinical

05 Side effects

Effect	Severity	Frequency	Evidence	Countermeasures
HPTA suppressionStrong suppression expected from a potent 19-nor androgen.	Severe	Expected	Preclinical
Progestogenic effects19-nor steroids often carry progestin activity affecting libido and gynecomastia risk.	Moderate	Uncertain	Preclinical

06 Legal status

United States

Likely captured as an anabolic steroid analogue

May fall under analogue provisions depending on exact structure. · as of Jan 2026

07 References

Androgenic-anabolic activity of 19-nor steroids (historical bioassay review)Steroids, historical

08 Discussion0 comments

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This page is reference information, not medical advice. Doses and protocols are documented as they appear in the clinical literature and in practice — describing them is not a recommendation to use them. Countermeasures listed here are not a substitute for a physician. Legal status varies by jurisdiction and changes.