Chlorodehydromethylandrostenediol
Chlorodehydromethylandrostenediol (CDMA, marketed as 'Halodrol' prohormone versions and 'Promagnon') is the 3-beta-hydroxy diol precursor to 4-chlorodehydromethyltestosterone (oral turinabol). It is an orally active designer prohormone that converts partially in vivo toward a turinabol-like non-aromatising androgen, giving dry lean gains with 17-alpha-alkylated hepatotoxicity and no human trial data.
01 Overview
CDMA (4-chloro-17alpha-methyl-androst-1,4-diene-3beta,17beta-diol) was one of the most widely sold 'Halodrol' prohormones. It is structurally the diol analogue of oral turinabol and undergoes partial conversion to the active ketone androgen, so the practical profile resembles a milder oral turinabol: dry, no aromatisation, and androgenic.
Despite branding overlap with turinabol, CDMA is a distinct molecule sold without any clinical evaluation. Its 17-alpha-methyl group makes it hepatotoxic, and adverse-event reporting for 'Halodrol' products includes cholestatic injury.
02 Mechanism
Prohormone that partially converts to a 4-chloro non-aromatising androgen binding the androgen receptor; 17-alpha-methylation gives oral activity; the 4-chloro group blocks aromatisation.
03 Dosing
| Tier | Dose | Route | Notes |
|---|---|---|---|
| Anecdotal | 50–100 mg/day | Oral | Grey-market prohormone dosing. |
Ester comparison
| Ester | Half-life | Injection freq. | Testosterone by mass |
|---|
04 Effects
| Effect | Magnitude | Evidence | |
|---|---|---|---|
| Dry lean mass gainTurinabol-like dry gains without water retention. | 2-4 kg reported | Anecdotal | |
| Strength increaseProgressive strength over 4-6 week runs. | modest | Anecdotal |
05 Side effects
| Effect | Severity | Frequency | Evidence | Countermeasures |
|---|---|---|---|---|
| Adverse lipidsHDL suppression typical of oral AAS. | Moderate | Common | Observational | |
| HPTA suppressionSuppresses endogenous testosterone. | Moderate | Universal | Observational | |
| HepatotoxicityCholestatic liver injury reported with Halodrol-type products. | Severe | Common | Observational |