Tuaminoheptane
Tuaminoheptane is an aliphatic amine originally used as a nasal decongestant that has appeared in pre-workout supplements as a stimulant. It is a sympathomimetic with a WADA ban in sport and little modern human safety data for oral supplement use.
01 Overview
Tuaminoheptane (2-aminoheptane) was marketed decades ago as an inhaled decongestant. Its structural similarity to other banned amines led to its appearance in grey-market pre-workouts, sometimes as an undeclared adulterant.
It raises blood pressure through vasoconstriction and is prohibited by WADA. Oral supplement use is not supported by safety data, and it shares the cardiovascular cautions of the aliphatic-amine stimulants.
02 Mechanism
Indirect sympathomimetic causing noradrenaline release and vasoconstriction, raising blood pressure.
03 Dosing
| Tier | Dose | Route | Notes |
|---|---|---|---|
| Found in products | 25–100 mg | Oral | Approximate amounts in supplements; no validated dose. |
04 Effects
| Effect | Magnitude | Evidence | |
|---|---|---|---|
| StimulationReported energy and focus similar to other amine stimulants. | Moderate | Anecdotal |
05 Side effects
| Effect | Severity | Frequency | Evidence | Countermeasures |
|---|---|---|---|---|
| OverstimulationJitteriness and anxiety. | Mild | Common | Anecdotal | |
| Elevated blood pressureVasoconstriction raises blood pressure. | Severe | Unquantified | Preclinical |