SARMInjectableSARMEster prodrugAndrogen receptor modulator

Testolone Enanthate (RAD-140 Ester)

Also known as RAD-140 enanthate · Testolone enanthate · Injectable RAD-140

Written by enwyReviewed 15 Jul 20261 sources0 comments

Testolone enanthate is a purported esterified, injectable prodrug of the SARM testolone (RAD-140), sold on the grey market as a longer-acting alternative to oral RAD-140. It is distinct from the marketed RAD-150 (a benzoate ester also sold as "testolone ester"). There is essentially no published human pharmacology for an enanthate ester of RAD-140.

01 Overview

The SARM RAD-140 (testolone) is a non-steroidal androgen receptor ligand with tissue-selective anabolic activity in preclinical models. "Testolone enanthate" refers to grey-market preparations claimed to attach an enanthate chain to RAD-140 to slow release after injection, mirroring the logic of steroid esters.

Unlike the oral RAD-140, which has at least early human exposure data via the enobosarm-era SARM programmes, an enanthate ester of RAD-140 has no meaningful published clinical or pharmacokinetic characterisation. Whatever anabolic effect it has is inferred from the parent SARM, and purity/identity of underground product is unverified.

02 Mechanism

As an ester prodrug, it is presumed to be cleaved to RAD-140, a non-steroidal selective androgen receptor modulator that activates the androgen receptor with relative selectivity for muscle and bone over prostate.

03 Dosing

Tier	Dose	Route	Notes
Anecdotal research use	10–20 mg/wk	IM	No validated human dosing; figures reflect underground practice for the parent SARM only.

Ester comparison

Ester	Half-life	Injection freq.	Testosterone by mass

04 Effects

Effect	Magnitude	Evidence
Increased lean massParent RAD-140 increases muscle mass in animal models; no controlled human data for the ester.	Model-dependent	Preclinical
Anabolic activity with partial androgen selectivityRAD-140 shows tissue-selective anabolic effects in preclinical work.	Preclinical	Preclinical

05 Side effects

Effect	Severity	Frequency	Evidence	Countermeasures
HPTA suppressionSARMs including RAD-140 suppress endogenous testosterone; users report reduced natural production.	Moderate	Common	Anecdotal
Hepatic strain / transaminase elevationRAD-140 has been linked to case reports of drug-induced liver injury.	Moderate	Uncommon	Anecdotal

06 Legal status

United States

Not approved; sold as research chemical

SARMs are not approved for human use and are prohibited in sport by WADA (S1.2). Subject to enforcement action as unapproved drugs. · as of Jan 2026

07 References

Discovery of RAD140, a nonsteroidal selective androgen receptor modulatorACS Medicinal Chemistry Letters, 2011

08 Discussion0 comments

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This page is reference information, not medical advice. Doses and protocols are documented as they appear in the clinical literature and in practice — describing them is not a recommendation to use them. Countermeasures listed here are not a substitute for a physician. Legal status varies by jurisdiction and changes.