PV-8
PV-8 (alpha-pyrrolidinoheptiophenone) is a synthetic cathinone stimulant of the pyrrolidinophenone family, a longer seven-carbon chain homologue of alpha-PVP. It appeared on the research-chemical market as a successor to banned pyrrolidinophenones. Human pharmacology is uncharacterised; reported effects are anecdotal and describe a potent, long-lasting stimulant with heavy redose pressure.
01 Overview
PV-8 is an alpha-pyrrolidinophenone ('pyrro') cathinone sold as a 'research chemical'. Extending the alkyl chain relative to alpha-PVP is reported to lengthen duration while retaining the potent, focused stimulant character of the series, with strong compulsive redosing.
The class hazards apply in full and are amplified in the potent pyrrolidinophenones: compulsive redosing, cardiovascular strain, harsh comedown and unknown neurotoxicity. There are no controlled human studies, so figures are approximate and drawn from user reports.
02 Mechanism
Potent selective inhibitor of dopamine and noradrenaline reuptake with little serotonergic action, typical of the alpha-pyrrolidinophenone cathinones.
03 Dosing
| Tier | Dose | Route | Notes |
|---|---|---|---|
| Common | 5–20 mg | Insufflated | Faster, stronger, highly compulsive. |
| Common | 10–30 mg | Oral | Anecdotal; potent, easy to overshoot. |
04 Effects
| Effect | Magnitude | Evidence | |
|---|---|---|---|
| StimulationStrong energy and wakefulness reported by users. | Anecdotal | ||
| Increased focusTask fixation typical of the pyrrolidinophenones. | Anecdotal | ||
| Appetite suppressionMarked reduction in hunger during effects. | Anecdotal |
05 Side effects
| Effect | Severity | Frequency | Evidence | Countermeasures |
|---|---|---|---|---|
| Compulsive redosingIntense urge to redose, driving multi-day binges. | Severe | Most users | Anecdotal | |
| Stimulant psychosisParanoia, agitation and hallucinations after prolonged use. | Severe | On binges | Unconfirmed | |
| Cardiovascular strainMarked tachycardia and hypertension. | Severe | Common | Unconfirmed |