Research chemicalStimulantResearch chemicalEntactogenSubstituted cathinone

Pentylone

Also known as Pentylone · bk-methyl-K · ba-methyl-K · methylenedioxypentedrone

Written by enwyReviewed 4 Aug 20262 sources0 comments

Pentylone is a substituted cathinone stimulant of the 'bath salts' family, structurally related to pentedrone and methylone. It combines stimulant and mild entactogenic effects and has appeared in poisonings and deaths, often mis-sold as or mixed with other cathinones. Human data is limited to case reports and forensic analysis.

01 Overview

Pentylone (bk-methyl-K, a methylenedioxy-substituted cathinone) is part of the second-generation synthetic cathinone wave. It has been detected in seized 'bath salt' and 'research chemical' products, sometimes as an adulterant or replacement for other cathinones.

Human knowledge is limited to emergency-department case reports, forensic toxicology and monitoring by drug agencies, including cases of severe agitation, cardiovascular events and death. Its stimulant-entactogen profile carries the class hazards of cardiovascular strain, compulsive redosing, harsh comedown and unknown long-term neurotoxicity.

02 Mechanism

Acts as a monoamine reuptake inhibitor and releasing agent affecting dopamine, noradrenaline and serotonin, characteristic of methylenedioxy-substituted cathinones.

03 Dosing

Tier	Dose	Route	Notes
Light	20–50 mg	Oral	Anecdotal; often mis-sold, so purity and identity are unreliable.
Common	20–70 mg	Insufflated	Harsh; faster onset drives heavy compulsive redosing.
Common	50–100 mg	Oral	Strong redosing tendency typical of cathinones.

04 Effects

Effect	Magnitude	Evidence
Stimulation and euphoriaEnergy, drive and euphoria typical of cathinone stimulants.	moderate-strong	Anecdotal
Mild entactogenic effectsSome empathogenic warmth from serotonergic activity, weaker than MDMA.		Anecdotal
Appetite suppressionReduced hunger during the active period.		Anecdotal

05 Side effects

Effect	Severity	Frequency	Evidence
Harsh comedown and unknown neurotoxicitySevere fatigue, low mood and anxiety after binges; long-term neurotoxic potential untested.	Moderate	Common	Unconfirmed
Cardiovascular strainTachycardia, hypertension and chest pain; implicated in agitation-related toxicity and deaths.	Severe	Common	Observational
Compulsive redosingCathinones are notorious for driving intense redosing binges.	Severe	Very common	Anecdotal

06 Legal status

Misuse of Drugs Act (cathinones)

Captured by the generic cathinone ban. · as of Jan 2026

United States

Not federally scheduled by name

Possible analogue under the Federal Analogue Act; some states control it. · as of Jan 2026

07 References

Pentylone: forensic and clinical toxicologyPubMed

Synthetic cathinones drug profileEUDA (European Union Drugs Agency)

08 Discussion0 comments

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This page is reference information, not medical advice. Doses and protocols are documented as they appear in the clinical literature and in practice — describing them is not a recommendation to use them. Countermeasures listed here are not a substitute for a physician. Legal status varies by jurisdiction and changes.