Roidipedia.Compound reference & reporting
05 AUG 2026
CompoundsAnabolic steroid Methylnortestosterone
Anabolic steroidAndrogen19-nortestosteroneAnabolic steroidOral17-alpha-alkylatedInvestigational

Methylnortestosterone

Also known as 17-methyl-19-nortestosterone · Methyl-nortestosterone · MENT oral relative

Methylnortestosterone (17alpha-methyl-19-nortestosterone, MENT's oral relative) is an orally active 19-nor androgen investigated in the context of male hormonal contraception via its acetate/enanthate injectable cousins. The 17-alpha-methylated oral form is a potent, non-aromatising (weakly aromatising) androgen with progestogenic activity, oral hepatotoxicity, and strong gonadotropin suppression.

01 Overview

Methylnortestosterone relates to the trestolone (MENT, 7-alpha-methyl-19-nortestosterone) research program aimed at hormonal male contraception, where its potent suppression of spermatogenesis is a desired effect. The 17-alpha-methylated oral analogue trades injectable delivery for oral activity at the cost of hepatic strain.

As a 19-nor compound it is progestogenic and only weakly aromatising; suppression is strong, which is precisely why the parent class was studied as a contraceptive. Human data on the specific oral methylated form are limited.

02 Mechanism

Potent 19-nor androgen-receptor agonist with progestogenic activity; 17-alpha-methylation confers oral activity; weak aromatisation.

03 Dosing

TierDoseRouteNotes
Anecdotal10–30 mg/dayOralNo approved human dose; anecdotal only.

Ester comparison

EsterHalf-lifeInjection freq.Testosterone by mass

04 Effects

EffectMagnitudeEvidence
Lean mass gainPotent 19-nor anabolic activity.modestAnecdotal
Improved recovery/well-beingReported androgenic well-being from the MENT-related class.unclearAnecdotal

05 Side effects

EffectSeverityFrequencyEvidenceCountermeasures
Hepatotoxicity17-alpha-methyl oral raises transaminases.SevereExpected for classPreclinical
Progestogenic side effectsLibido loss and possible gynecomastia.ModerateCommonPreclinical
Strong HPTA suppressionMarked suppression of spermatogenesis and testosterone (basis of contraceptive interest).SevereUniversalClinical

07 References

7alpha-methyl-19-nortestosterone (MENT) and related nortestosterones for male contraceptionJournal of Andrology / Contraception

08 Discussion0 comments

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