Research chemicalResearch chemicalPhenethylaminePsychedelic
Methallylescaline
Also known as MAL · 3-methallyloxy-4,5-dimethoxyphenethylamine
Methallylescaline (MAL) is a synthetic scaline psychedelic, the 3-methallyloxy analogue of mescaline. It is potent and long-acting with a strongly visual, sometimes stimulating profile, and has minimal human study.
01 Overview
Methallylescaline carries a methallyloxy group at the 3 position of mescaline. Reports describe intense visuals, emotional and sometimes stimulating effects, and a long duration on the order of 8-12 hours or more.
Evidence is anecdotal, from self-experiments and grey-market circulation. Higher-dose reports note pronounced stimulation and residual stimulation into the comedown. Safety is not established.
02 Mechanism
Serotonin 5-HT2A receptor agonist; the methallyloxy substitution increases potency relative to mescaline.
03 Dosing
| Tier | Dose | Route | Notes |
|---|---|---|---|
| Threshold | 10–20 mg | Oral | |
| Common | 20–60 mg | Oral | PiHKAL range. |
| Strong | 60–80 mg | Oral |
04 Effects
| Effect | Magnitude | Evidence | |
|---|---|---|---|
| Strong visual enhancementIntense colour and geometry. | Anecdotal | ||
| StimulationEnergetic, sometimes restless quality at higher doses. | Anecdotal | ||
| Long durationExtended experience with lingering comedown. | 8-14 h | Anecdotal |
05 Side effects
| Effect | Severity | Frequency | Evidence | Countermeasures |
|---|---|---|---|---|
| NauseaOnset queasiness. | Mild | Common | Anecdotal | |
| Insomnia and restlessnessDifficulty sleeping due to the stimulating tail. | Mild | Common | Anecdotal | |
| AnxietyAnxiety at higher doses. | Moderate | Dose-dependent | Anecdotal |
06 Legal status
United Kingdom
Class A
as of Jan 2026
United States
Unscheduled
Possible Analogue Act coverage. · as of Jan 2026
07 References
PiHKAL: A Chemical Love Story (Methallylescaline entry)Shulgin A. & Shulgin A., 1991
08 Discussion0 comments
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This page is reference information, not medical advice. Doses and protocols are documented as they appear in the clinical literature and in practice — describing them is not a recommendation to use them. Countermeasures listed here are not a substitute for a physician. Legal status varies by jurisdiction and changes.