Research chemicalStimulantSympathomimetic amineEthanolamine
Halostachine
Also known as N-methylphenylethanolamine · N-methyl-beta-phenylethanolamine
Halostachine (N-methylphenylethanolamine) is a synephrine-like sympathomimetic amine found in the grass Halostachys and sold in fat-burners as a mild adrenergic stimulant. Human safety and efficacy data are almost nonexistent.
01 Overview
Halostachine is structurally similar to synephrine and phenylephrine, an ethanolamine sympathomimetic. It appears in some thermogenic and pre-workout products as a stimulant and appetite modulator.
There is very little human research; most information is extrapolated from its adrenergic structure and animal work. It shares the general cardiovascular caution of the synephrine class.
02 Mechanism
Beta- and alpha-adrenergic agonist activity similar to synephrine, promoting mild lipolysis and cardiovascular stimulation.
03 Dosing
| Tier | Dose | Route | Notes |
|---|---|---|---|
| Common | 20–50 mg | Oral | Approximate labelled dose; not standardised. |
04 Effects
| Effect | Magnitude | Evidence | |
|---|---|---|---|
| Mild thermogenesisAdrenergic activity may modestly raise metabolic rate. | Mild | Preclinical |
05 Side effects
| Effect | Severity | Frequency | Evidence | Countermeasures |
|---|---|---|---|---|
| Cardiovascular stimulationPossible increases in heart rate and blood pressure. | Mild | Unquantified | Preclinical | |
| AnxietyOverstimulation and restlessness possible. | Mild | Unquantified | Anecdotal |
06 Legal status
United States
Disputed dietary ingredient status
as of Jan 2026
07 References
Halostachine and synephrine-type adrenergic aminesPubMed
08 Discussion0 comments
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This page is reference information, not medical advice. Doses and protocols are documented as they appear in the clinical literature and in practice — describing them is not a recommendation to use them. Countermeasures listed here are not a substitute for a physician. Legal status varies by jurisdiction and changes.