Roidipedia.Compound reference & reporting
06 AUG 2026
CompoundsResearch chemical ETH-LAD
Research chemicalResearch chemicalPsychedelicLysergamide

ETH-LAD

Also known as 6-ethyl-6-nor-LSD

ETH-LAD (6-ethyl-6-nor-LSD) is a lysergamide analogue of LSD in which the N6 methyl group is replaced by ethyl. It is somewhat more potent than LSD and reported to be more visual, with a notable body load and vasoconstriction. Active doses are in the microgram range. Human data are almost entirely anecdotal.

01 Overview

ETH-LAD is a semi-synthetic lysergamide first described by Shulgin and a 5-HT2A agonist. Replacing the N6 methyl of LSD with an ethyl group modestly increases potency and, by user accounts, shifts the experience toward stronger visuals and a heavier body load. It is active in micrograms and usually taken orally or sublingually.

Reports frequently mention pronounced physical effects, including vasoconstriction and body tension, sometimes more than with LSD at equivalent intensity. As a lysergamide research chemical, potency varies between batches and blotter dosing is imprecise, making titration difficult. Formal human pharmacology is lacking.

02 Mechanism

Lysergamide agonist at serotonin 5-HT2A (and other serotonin) receptors; N6-ethyl substitution modestly increases potency relative to LSD.

03 Dosing

TierDoseRouteNotes
Threshold20–40 mcgOralActive in micrograms; slightly more potent than LSD.
Common50–100 mcgSublingualReported more visual than LSD; individual sensitivity varies.
Strong100–200 mcgOralStrong visuals with pronounced body load and vasoconstriction.

04 Effects

EffectMagnitudeEvidence
Strong visual psychedeliaReported as more visually intense than LSD at comparable doses.strongAnecdotal
Mood and cognitive alterationEmotional and introspective effects typical of lysergamides.Anecdotal
Body loadNoticeable physical tension and stimulation reported.Anecdotal

05 Side effects

EffectSeverityFrequencyEvidenceCountermeasures
Vasoconstriction and body tensionPeripheral vasoconstriction and muscle tension reported, sometimes more than with LSD.ModerateCommonAnecdotal
Anxiety and difficult experiencesOverwhelming states can occur, especially with imprecise dosing.ModerateCommonAnecdotal

07 References

Shulgin A, Shulgin A. TiHKAL: The ContinuationTransform Press, 1997
ETH-LAD entryPsychonautWiki

08 Discussion0 comments

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This page is reference information, not medical advice. Doses and protocols are documented as they appear in the clinical literature and in practice — describing them is not a recommendation to use them. Countermeasures listed here are not a substitute for a physician. Legal status varies by jurisdiction and changes.