Research chemicalResearch chemicalPsychedelicTryptamine

DiPT (auditory distortion)

Also known as N,N-diisopropyltryptamine · DiPT

Written by enwyReviewed 4 Aug 20262 sources0 comments

DiPT (N,N-diisopropyltryptamine) is a synthetic tryptamine described by Shulgin that is unusual for producing predominantly auditory rather than visual effects, notably a downward shift and distortion of perceived pitch. It is used non-medically. Human data are anecdotal; potency and safety are uncharacterised, with wide individual dose variation.

01 Overview

DiPT is distinctive among psychedelics for its pronounced auditory effects: users report that sounds and voices are shifted downward in pitch and distorted, with relatively minor visual alteration. This unusual profile has made it a subject of curiosity.

No controlled human studies exist; effects and doses are known only from self-reports. The auditory distortion can persist for hours and occasionally longer, and dose responses vary between individuals. Psychological discomfort from the disorienting auditory changes is possible.

02 Mechanism

Serotonin 5-HT2A receptor agonist (classical psychedelic mechanism); the basis of its selective auditory effects is not established.

03 Dosing

Tier	Dose	Route	Notes
Threshold	15–25 mg	Oral	Approximate; from user reports.
Common	25–75 mg	Oral	Onset ~30-60 min; auditory effects can last many hours. Not clinically validated.
Strong	75–100 mg	Oral	Higher risk of prolonged, disorienting auditory distortion.

04 Effects

Effect	Magnitude	Evidence
Auditory distortionDownward pitch shift and distortion of sounds and voices, the hallmark effect.	characteristic	Anecdotal
Minimal visual effectsVisuals reported to be mild compared with most psychedelics.		Anecdotal
Altered cognitionMild changes in thought and mood reported.		Anecdotal

05 Side effects

Effect	Severity	Frequency	Evidence
NauseaGastrointestinal discomfort during onset.	Mild	Common	Anecdotal
Cardiovascular stimulationIncreased heart rate and blood pressure.	Mild	Common	Anecdotal
Disorientation and distress from auditory changesThe unusual and persistent auditory distortion can be disorienting or distressing.	Moderate	Common	Anecdotal

06 Legal status

United Kingdom

Class A / tryptamine controls

Covered by UK tryptamine provisions. · as of Jan 2026

United States

Not federally scheduled by name; possible Federal Analogue Act exposure. · as of Jan 2026

07 References

TiHKAL: The Continuation (DiPT entry)Shulgin & Shulgin, 1997

New psychoactive substances monitoringEUDA (formerly EMCDDA)

08 Discussion0 comments

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This page is reference information, not medical advice. Doses and protocols are documented as they appear in the clinical literature and in practice — describing them is not a recommendation to use them. Countermeasures listed here are not a substitute for a physician. Legal status varies by jurisdiction and changes.