alpha-PBP
alpha-PBP (alpha-pyrrolidinobutiophenone) is a pyrrolidine synthetic cathinone in the pyrovalerone family, a shorter-chain homologue of alpha-PVP. Sold as a research chemical, it is a potent dopamine reuptake inhibitor with strong compulsive potential. Human data is minimal and all information is anecdotal.
01 Overview
alpha-PBP is a butyrophenone homologue of alpha-PVP, marketed as a legal-grey stimulant. The shorter alkyl chain makes it somewhat less potent than alpha-PVP but with a similar potent, focused and highly compulsive stimulant character.
As a pyrrolidine cathinone it carries a heightened risk of compulsive redosing and binge use, plus cardiovascular strain, comedown and unknown neurotoxicity. No controlled human studies exist; figures are approximate.
02 Mechanism
Potent, selective noradrenaline-dopamine reuptake inhibitor at the dopamine and noradrenaline transporters, characteristic of the pyrovalerone/alpha-PVP family.
03 Dosing
| Tier | Dose | Route | Notes |
|---|---|---|---|
| Common | 7–20 mg | Insufflated | Very compulsive. |
| Common | 10–30 mg | Oral | Anecdotal; potent, start low. |
04 Effects
| Effect | Magnitude | Evidence | |
|---|---|---|---|
| Intense stimulationStrong energy and focus. | Anecdotal | ||
| EuphoriaDopaminergic mood elevation. | Anecdotal | ||
| Appetite suppressionMarked hunger reduction. | Anecdotal |
05 Side effects
| Effect | Severity | Frequency | Evidence | Countermeasures |
|---|---|---|---|---|
| Compulsive redosingStrong redosing compulsion typical of pyrrolidine cathinones. | Severe | Near universal | Anecdotal | |
| Cardiovascular strainTachycardia and hypertension. | Severe | Common | Unconfirmed | |
| Stimulant psychosisParanoia and hallucinations after binges and sleep loss. | Severe | Uncommon | Unconfirmed |