4-MTMC
4-MTMC (4-methylthiomethcathinone) is a synthetic cathinone stimulant bearing a methylthio group at the para position of the aromatic ring. It is a niche research-chemical analogue of methcathinone with essentially no published human pharmacology. All reported effects are anecdotal and describe a mephedrone-like stimulant character.
01 Overview
4-MTMC is a ring-substituted cathinone sold as a 'research chemical' with no approved medical use. The para methylthio substituent distinguishes it from mephedrone; users report a broadly similar stimulant and mildly euphoric profile that encourages compulsive redosing.
The class hazards apply in full: compulsive redosing, cardiovascular strain, harsh comedown and unknown neurotoxicity. There are no controlled human studies, so figures are approximate and drawn from user reports.
02 Mechanism
Presumed monoamine releaser and reuptake inhibitor at dopamine, noradrenaline and serotonin transporters, analogous to other 4-substituted methcathinones.
03 Dosing
| Tier | Dose | Route | Notes |
|---|---|---|---|
| Common | 50–120 mg | Insufflated | Faster onset, more compulsive. |
| Common | 100–200 mg | Oral | Anecdotal only. |
04 Effects
| Effect | Magnitude | Evidence | |
|---|---|---|---|
| StimulationEnergy and alertness reported by users. | Anecdotal | ||
| Mild euphoriaMood lift and sociability. | Anecdotal | ||
| Appetite suppressionReduced hunger during effects. | Anecdotal |
05 Side effects
| Effect | Severity | Frequency | Evidence | Countermeasures |
|---|---|---|---|---|
| Compulsive redosingUrge to redose repeatedly, driving binges. | Moderate | Most users | Anecdotal | |
| Cardiovascular strainTachycardia and hypertension typical of the class. | Severe | Common | Unconfirmed | |
| Comedown and low moodFatigue and depressed mood after use. | Moderate | Common | Anecdotal |