Research chemicalPsychedelicTryptamineSerotonergicPsilocin analog
4-HO-pyr-T / 4-HO-PT (4-Hydroxy tryptamine analog)
Also known as 4-Hydroxy-PT · 4-Hydroxy propyltryptamine analog
4-HO-PT refers to 4-hydroxy propyl-substituted tryptamine psilocin analogs. Very obscure research chemicals with no formal human data; effects presumed psilocybin-like by analogy.
01 Overview
4-HO-PT sits in the family of 4-hydroxy psilocin analogs alongside better-known compounds such as 4-HO-DPT and 4-HO-MET. It appears only rarely and has no published pharmacology.
As with other 4-hydroxy tryptamines it is presumed orally active and psilocybin-like, but no safety, potency or pharmacokinetic data exist. All figures below are anecdotal and highly uncertain.
02 Mechanism
Presumed serotonin 5-HT2A receptor agonist like psilocin and its analogs.
03 Dosing
| Tier | Dose | Route | Notes |
|---|---|---|---|
| Common (reported) | 15–35 mg | Oral | Highly uncertain; anecdotal only. |
04 Effects
| Effect | Magnitude | Evidence | |
|---|---|---|---|
| Psilocybin-like psychedeliaPresumed psilocin-analog perceptual effects; unverified. | unknown | Unconfirmed | |
| Mood alterationReported anecdotally; not characterised. | unknown | Unconfirmed |
05 Side effects
| Effect | Severity | Frequency | Evidence | Countermeasures |
|---|---|---|---|---|
| Unknown toxicityNo safety data exists; harm cannot be excluded. | Moderate | Unknown | Unconfirmed | |
| AnxietyDifficult psychological experiences possible. | Moderate | Unknown | Unconfirmed |
06 Legal status
United Kingdom
Class A (tryptamine generic clause)
as of Jan 2026
United States
Possibly Analogue Act
as of Jan 2026
07 References
Shulgin A, Shulgin A. TIHKAL: The Continuation (4-hydroxytryptamine series)Transform Press, 1997
08 Discussion0 comments
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This page is reference information, not medical advice. Doses and protocols are documented as they appear in the clinical literature and in practice — describing them is not a recommendation to use them. Countermeasures listed here are not a substitute for a physician. Legal status varies by jurisdiction and changes.