Research chemicalPsychedelicTryptamineSerotonergicPsilocin analog
4-AcO-DPT (4-Acetoxy-N,N-dipropyltryptamine)
Also known as 4-Acetoxy-DPT · 4-Acetoxy-N,N-dipropyltryptamine
4-AcO-DPT is the 4-acetoxy ester of DPT, presumed to act as a prodrug for 4-HO-DPT. It is a psychedelic research chemical reported to give a psilocybin-like experience with a distinct character. No formal human data exists.
01 Overview
4-AcO-DPT extends the 4-acetoxy tryptamine series to the dipropyl analog. Like 4-AcO-DMT and 4-AcO-DET it is presumed to be hydrolysed in the body to its active 4-hydroxy form (4-HO-DPT).
Users report a psychedelic experience often described as more physical or unusual than psilocybin. No controlled studies exist, so dosing and safety information is anecdotal.
02 Mechanism
Likely a prodrug hydrolysed to 4-HO-DPT, a serotonin 5-HT2A receptor agonist.
03 Dosing
| Tier | Dose | Route | Notes |
|---|---|---|---|
| Light (reported) | 15–25 mg | Oral | Anecdotal. |
| Common (reported) | 25–50 mg | Oral | Anecdotal. |
04 Effects
| Effect | Magnitude | Evidence | |
|---|---|---|---|
| Psychedelic experienceVisuals and altered cognition, sometimes with a distinctive physical character. | moderate | Anecdotal | |
| IntrospectionReflective or emotionally intense states reported. | variable | Anecdotal |
05 Side effects
| Effect | Severity | Frequency | Evidence | Countermeasures |
|---|---|---|---|---|
| AnxietyDifficult experiences at higher doses. | Moderate | Common | Anecdotal | |
| Nausea and body loadPhysical discomfort during onset reported with dipropyl tryptamines. | Moderate | Common | Anecdotal |
06 Legal status
United Kingdom
Class A (tryptamine generic clause)
as of Jan 2026
United States
Possibly Analogue Act
as of Jan 2026
07 References
Shulgin A, Shulgin A. TIHKAL: The Continuation (4-acetoxy/4-hydroxy tryptamines)Transform Press, 1997
08 Discussion0 comments
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This page is reference information, not medical advice. Doses and protocols are documented as they appear in the clinical literature and in practice — describing them is not a recommendation to use them. Countermeasures listed here are not a substitute for a physician. Legal status varies by jurisdiction and changes.