Roidipedia.Compound reference & reporting
05 AUG 2026
CompoundsResearch chemical 3-MeO-PCMo
Research chemicalDissociativeArylcyclohexylamineNMDA antagonistPCP analogue

3-MeO-PCMo

Also known as 3-methoxy-PCMo · 3-MeO-PCMo

3-MeO-PCMo is a novel arylcyclohexylamine dissociative research chemical, a morpholine-ring PCP analogue bearing a 3-methoxy group. It is reported as notably weaker and longer-acting than related dissociatives, with no clinical study and essentially no human toxicology.

01 Overview

3-MeO-PCMo replaces the piperidine of PCP with a morpholine ring and adds a 3-methoxy substituent. Anecdotally it is described as a milder, longer, more sedating dissociative, requiring larger doses than 3-MeO-PCP or 3-MeO-PCE.

As with the rest of this family, there are no controlled human studies. Its lower potency does not make it safe: purity, exact dose-response and organ toxicity are all unknown, and it shares the bladder and dependence concerns of the broader dissociative class.

02 Mechanism

Non-competitive NMDA receptor antagonist of the PCP class; morpholine substitution lowers potency relative to piperidine analogues.

03 Dosing

TierDoseRouteNotes
Anecdotal (unverified)40–120 mgOralAnecdotal only; described as weaker and longer than 3-MeO-PCP.

04 Effects

EffectMagnitudeEvidence
Sedating dissociationMild, long-lasting dissociation with pronounced sedation reported by users.unquantifiedAnecdotal
AnalgesiaBody numbing typical of dissociatives, reported anecdotally.unquantifiedAnecdotal

05 Side effects

EffectSeverityFrequencyEvidenceCountermeasures
Prolonged sedation / motor impairmentLong duration can leave users impaired for many hours.ModerateUnknownAnecdotal
Unknown toxicologyNo human safety data; bladder and dependence risks of the class may apply.ModerateUnknownUnconfirmed

07 References

Arylcyclohexylamine NPS: identification and pharmacologyDrug Test Anal, 2019

08 Discussion0 comments

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