Roidipedia.Compound reference & reporting
06 AUG 2026
CompoundsCompare Mesterolone (Proviron, oral DHT) vs Drostanolone Propionate (Masteron)
Comparison

Mesterolone (Proviron, oral DHT) vs Drostanolone Propionate (Masteron)

A neutral, evidence-rated side-by-side of Mesterolone (Proviron, oral DHT) and Drostanolone Propionate (Masteron). Figures are typical reference values, not recommendations.

Mesterolone (Proviron, oral DHT)Drostanolone Propionate (Masteron)
TypeAnabolic steroidAnabolic steroid
Evidence levelStudiedEmerging
Primary classAndrogenAndrogen
Half-life~12-13 hours~2-3 days (propionate ester)
Typical dose50–100 mg/day300–400 mg/wk
Anabolic : androgenic40 : 10062 : 25
AromatisesNoNo
HepatotoxicityLowLow
HPTA suppressionModerateSevere
Documented effects33
Documented side effects33

Mesterolone (Proviron, oral DHT)

An orally active DHT derivative (Proviron) used clinically for androgen deficiency and male infertility. It is weakly anabolic but a strong androgen-receptor binder and a modest anti-oestrogen, so it is used less to build muscle than to raise free testosterone by displacing it from SHBG, add a 'dry' hardening effect, and support libido. Not 17-alpha-alkylated, so low liver toxicity.

Full Mesterolone (Proviron, oral DHT) page →

Drostanolone Propionate (Masteron)

A DHT-derived, non-aromatising injectable (2-alpha-methyl-dihydrotestosterone) historically used to treat breast cancer for its anti-oestrogenic effect. In bodybuilding it is valued for a hard, dry, defined look near contest time rather than raw mass, with a short propionate ester requiring frequent injection. Androgenic side effects (hair loss, acne) predominate; oestrogenic effects are essentially absent.

Full Drostanolone Propionate (Masteron) page →
Reference information, not medical advice.